Enhancement of HSA-pFSHβ production by disrupting YPS1 and supplementing N-acetyl-L-cysteine in Pichia pastoris

INTRODUCTION: Pichia pastoris is widely used for the production of recombinant proteins, but the low production efficiency hinders its wide application in biopharmaceuticals. Moreover, many biopharmaceutical-like proteins are accompanied by degradation during secretory expression in P. pastoris. OBJ...

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Detalles Bibliográficos
Autores principales: Luo, Gang, Geng, Zijian, Kuerban, Buayisham, Xu, Yingqing, Yang, Jingjing, Liu, Jiying, Li, Muwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810807/
https://www.ncbi.nlm.nih.gov/pubmed/36620033
http://dx.doi.org/10.3389/fmicb.2022.998647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810807/
https://www.ncbi.nlm.nih.gov/pubmed/36620033
http://dx.doi.org/10.3389/fmicb.2022.998647

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