A spike-trimer protein-based tetravalent COVID-19 vaccine elicits enhanced breadth of neutralization against SARS-CoV-2 Omicron subvariants and other variants

Multivalent vaccines combining crucial mutations from phylogenetically divergent variants could be an effective approach to defend against existing and future SARS-CoV-2 variants. In this study, we developed a tetravalent COVID-19 vaccine SCTV01E, based on the trimeric Spike protein of SARS-CoV-2 va...

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Detalles Bibliográficos
Autores principales: Wang, Rui, Huang, Hongpeng, Yu, Chulin, Sun, Chunyun, Ma, Juan, Kong, Desheng, Lin, Yalong, Zhao, Dandan, Zhou, Shaozheng, Lu, Jianbo, Cao, Sai, Zhang, Yanjing, Luo, Chunxia, Li, Xuefeng, Wang, Yang, Xie, Liangzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science China Press 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811042/
https://www.ncbi.nlm.nih.gov/pubmed/36598621
http://dx.doi.org/10.1007/s11427-022-2207-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811042/
https://www.ncbi.nlm.nih.gov/pubmed/36598621
http://dx.doi.org/10.1007/s11427-022-2207-7

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