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Reduced BDNF expression in the auditory cortex contributed to neonatal pain-induced hearing impairment and dendritic pruning deficiency in mice

INTRODUCTION: Procedural pain in neonates is associated with impaired neurodevelopment. Whether hearing development is impaired, however, remains unknown. This study examined potential cause-and-effect relationship between neonatal pain and subsequent hearing loss in mice. METHODS: Male C57BL/6J mou...

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Detalles Bibliográficos
Autores principales: Li, Nanqi, Chen, Bing, Jia, Gaogan, Xu, Rui, Xia, Ying, Lai, Chuijin, Li, Gang, Li, Wenxian, Han, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811087/
https://www.ncbi.nlm.nih.gov/pubmed/36384877
http://dx.doi.org/10.1136/rapm-2022-103621