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Extracellular Vesicle-Mediated Transfer of LncRNA IGFL2-AS1 Confers Sunitinib Resistance in Renal Cell Carcinoma

Sunitinib resistance remains a serious challenge to the treatment of advanced and metastatic renal cell carcinoma (RCC), yet the mechanisms underlying this resistance are not fully understood. Here, we report that the long noncoding RNA IGFL2-AS1 is a driver of therapy resistance in RCC. IGFL2-AS1 w...

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Detalles Bibliográficos
Autores principales: Pan, Yihui, Lu, Xuanxuan, Shu, Guannan, Cen, Junjie, Lu, Jun, Zhou, Mi, Huang, Kangbo, Dong, Jiaqi, Li, Jiaying, Lin, Haishan, Song, Hongde, Xu, Quanhui, Han, Hui, Chen, Zhenhua, Chen, Wei, Luo, Junhang, Wei, Jinhuan, Zhang, Jiaxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811158/
https://www.ncbi.nlm.nih.gov/pubmed/36264173
http://dx.doi.org/10.1158/0008-5472.CAN-21-3432