Article title: Transcriptional profiling efficacy to define biological activity similarity for cosmetic ingredients’ safety assessment based on next-generation read-across

The objective of this work was to use transcriptional profiling to assess the biological activity of structurally related chemicals to define their biological similarity and with that, substantiate the validity of a read-across approach usable in risk assessment. Two case studies are presented, one...

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Detalles Bibliográficos
Autores principales: Naciff, Jorge M., Shan, Yuquing K., Wang, Xiaohong, Daston, George P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Toxicology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811170/
https://www.ncbi.nlm.nih.gov/pubmed/36618549
http://dx.doi.org/10.3389/ftox.2022.1082222

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811170/
https://www.ncbi.nlm.nih.gov/pubmed/36618549
http://dx.doi.org/10.3389/ftox.2022.1082222

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