Integrated flow cytometry and sequencing to reconstruct evolutionary patterns from dysplasia to acute myeloid leukemia

Clonal evolution in acute myeloid leukemia (AML) originates long before diagnosis and is a dynamic process that may affect survival. However, it remains uninvestigated during routine diagnostic workups. We hypothesized that the mutational status of bone marrow dysplastic cells and leukemic blasts, a...

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Detalles Bibliográficos
Autores principales: Simoes, Catia, Chillon, Maria-Carmen, Martínez-Cuadrón, David, Calasanz, Maria-José, Vridiales, María-Belén, Vazquez, Iria, Hernández-Ruano, Montserrat, Ariceta, Beñat, Aguirre-Ruiz, Paula, Burgos, Leire, Alignani, Diego, Sarvide, Sarai, Villar, Sara, Pierola, Ana Alfonso, Prosper, Felipe, Ayala, Rosa, Martínez-López, Joaquin, Bergua Burgues, Juan Miguel, Vives, Susana, Perez-Simon, Jose A., Garcia-Fortes, Maria, Bernal del Castillo, Teresa, Colorado, Mercedes, Olave, Mayte, Rodríguez-Gutiérrez, Juan I., Labrador, Jorge, González, Marcos, San-Miguel, Jesús F., Sanz, Miguel Ángel, Montesinos, Pau, Paiva, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society of Hematology 2022
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811200/
https://www.ncbi.nlm.nih.gov/pubmed/36240453
http://dx.doi.org/10.1182/bloodadvances.2022008141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811200/
https://www.ncbi.nlm.nih.gov/pubmed/36240453
http://dx.doi.org/10.1182/bloodadvances.2022008141

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