Acetylation of the nuclear localization signal in Ku70 diminishes the interaction with importin-α

Proteins are functionally regulated by various types of posttranslational modifications (PTMs). Ku, a heterodimer complex of Ku70 and Ku80 subunits, participates in DNA repair processes. Ku is distributed not only in the nucleus but also in the cytoplasm, suggesting that the function of Ku is regula...

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Detalles Bibliográficos
Autores principales: Fujimoto, Hirofumi, Ikuta, Togo, Koike, Aki, Koike, Manabu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811216/
https://www.ncbi.nlm.nih.gov/pubmed/36620088
http://dx.doi.org/10.1016/j.bbrep.2022.101418

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811216/
https://www.ncbi.nlm.nih.gov/pubmed/36620088
http://dx.doi.org/10.1016/j.bbrep.2022.101418

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