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Acetylation of the nuclear localization signal in Ku70 diminishes the interaction with importin-α
Proteins are functionally regulated by various types of posttranslational modifications (PTMs). Ku, a heterodimer complex of Ku70 and Ku80 subunits, participates in DNA repair processes. Ku is distributed not only in the nucleus but also in the cytoplasm, suggesting that the function of Ku is regula...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811216/ https://www.ncbi.nlm.nih.gov/pubmed/36620088 http://dx.doi.org/10.1016/j.bbrep.2022.101418 |