Increased expression of the ectoenzyme CD38 in peripheral blood plasmablasts and plasma cells of patients with systemic sclerosis

OBJECTIVE: CD38 is a type II glycoprotein highly expressed on plasmablasts and on short- and long-lived plasma cells, but weakly expressed by lymphoid, myeloid, and non-hematopoietic cells. CD38 is a target for therapies aimed at depleting antibody-producing plasma cells. Systemic sclerosis (SSc) is...

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Detalles Bibliográficos
Autores principales: Agarbati, S., Benfaremo, D., Viola, N., Paolini, C., Svegliati Baroni, S., Funaro, A., Moroncini, G., Malavasi, F., Gabrielli, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811259/
https://www.ncbi.nlm.nih.gov/pubmed/36618427
http://dx.doi.org/10.3389/fimmu.2022.1072462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811259/
https://www.ncbi.nlm.nih.gov/pubmed/36618427
http://dx.doi.org/10.3389/fimmu.2022.1072462

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