Triplex-forming oligonucleotides as an anti-gene technique for cancer therapy

Triplex-forming oligonucleotides (TFOs) can bind to the major groove of double-stranded DNA with high specificity and affinity and inhibit gene expression. Triplex-forming oligonucleotides have gained prominence because of their potential applications in antigene therapy. In particular, the target s...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Chun, Zhou, Zunzhen, Ren, Chao, Deng, Yi, Peng, Feng, Wang, Qiongfen, Zhang, Hong, Jiang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811266/
https://www.ncbi.nlm.nih.gov/pubmed/36618947
http://dx.doi.org/10.3389/fphar.2022.1007723

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811266/
https://www.ncbi.nlm.nih.gov/pubmed/36618947
http://dx.doi.org/10.3389/fphar.2022.1007723

Ejemplares similares