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A natural carotenoid crocin exerts antidepressant action by promoting adult hippocampal neurogenesis through Wnt/β-catenin signaling

INTRODUCTION: Adult hippocampal neurogenesis (AHN) is acknowledged to play a critical role in depression. Emerging evidence suggests that the Wnt/β-catenin pathway can modulate hippocampal neurogenesis. Crocin, a natural carotenoid, possesses antidepressant property. Yet, how it affects neurogenesis...

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Detalles Bibliográficos
Autores principales: Tao, Weiwei, Ruan, Jie, Wu, Ruyan, Zhao, Min, Zhao, Tong, Qi, Mingming, Yau, Sonata S.Y., Yao, Guangda, Zhang, Hongru, Hu, Yue, Chen, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811320/
https://www.ncbi.nlm.nih.gov/pubmed/36585110
http://dx.doi.org/10.1016/j.jare.2022.02.015