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iNOS contributes to heart failure with preserved ejection fraction through mitochondrial dysfunction and Akt S-nitrosylation

INTRODUCTION: Despite the high morbidity and mortality of heart failure with preserved fraction (HFpEF), there are currently no effective therapies for this condition. Moreover, the pathophysiological basis of HFpEF remains poorly understood. OBJECTIVE: The aim of the present study was to investigat...

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Detalles Bibliográficos
Autores principales: Guo, Yongzheng, Wen, Junjie, He, An, Qu, Can, Peng, Yuce, Luo, Suxin, Wang, Xiaowen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811328/
https://www.ncbi.nlm.nih.gov/pubmed/36585107
http://dx.doi.org/10.1016/j.jare.2022.03.003