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Upregulation of Superenhancer‐Driven LncRNA FASRL by USF1 Promotes De Novo Fatty Acid Biosynthesis to Exacerbate Hepatocellular Carcinoma

Superenhancers drive abnormal gene expression in tumors and promote malignancy. However, the relationship between superenhancer‐associated long noncoding RNA (lncRNA) and abnormal metabolism is unknown. This study identifies a novel lncRNA, fatty acid synthesis‐related lncRNA (FASRL), whose expressi...

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Detalles Bibliográficos
Autores principales: Peng, Jiang‐Yun, Cai, Dian‐Kui, Zeng, Ren‐Li, Zhang, Chao‐Yang, Li, Guan‐Cheng, Chen, Si‐Fan, Yuan, Xiao‐Qing, Peng, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811444/
https://www.ncbi.nlm.nih.gov/pubmed/36307901
http://dx.doi.org/10.1002/advs.202204711