Molecular Dynamics Simulations of Self-Assembling Colloids in Fed-State Human Intestinal Fluids and Their Solubilization of Lipophilic Drugs

[Image: see text] Bioavailability of oral drugs often depends on how soluble the active pharmaceutical ingredient is in the fluid present in the small intestine. For efficient drug discovery and development, computational tools are needed for estimating this drug solubility. In this paper, we examin...

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Detalles Bibliográficos
Autores principales: Parrow, Albin, Larsson, Per, Augustijns, Patrick, Bergström, Christel A. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811461/
https://www.ncbi.nlm.nih.gov/pubmed/36350845
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811461/
https://www.ncbi.nlm.nih.gov/pubmed/36350845
http://dx.doi.org/10.1021/acs.molpharmaceut.2c00710

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