Selectivity and stability of N-terminal targeting protein modification chemistries

Protein N-termini provide uniquely reactive motifs for single site protein modification. Though a number of reactions have been developed to target this site, the selectivity, generality, and stability of the conjugates formed has not been studied. We have therefore undertaken a comprehensive compar...

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Detalles Bibliográficos
Autores principales: Barber, Lydia J., Yates, Nicholas D. J., Fascione, Martin A., Parkin, Alison, Hemsworth, Glyn R., Genever, Paul G., Spicer, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: RSC 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811658/
https://www.ncbi.nlm.nih.gov/pubmed/36685256
http://dx.doi.org/10.1039/d2cb00203e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811658/
https://www.ncbi.nlm.nih.gov/pubmed/36685256
http://dx.doi.org/10.1039/d2cb00203e

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