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Analysis of tripartite Synaptotagmin‐1‐SNARE‐complexin‐1 complexes in solution

Characterizing interactions of Synaptotagmin‐1 with the SNARE complex is crucial to understand the mechanism of neurotransmitter release. X‐ray crystallography revealed how the Synaptotagmin‐1 C(2)B domain binds to the SNARE complex through a so‐called primary interface and to a complexin‐1‐SNARE co...

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Detalles Bibliográficos
Autores principales: Jaczynska, Klaudia, Esquivies, Luis, Pfuetzner, Richard A., Alten, Baris, Brewer, Kyle D., Zhou, Qiangjun, Kavalali, Ege T., Brunger, Axel T., Rizo, Josep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811660/
https://www.ncbi.nlm.nih.gov/pubmed/36305864
http://dx.doi.org/10.1002/2211-5463.13503