Lactate oxidase/catalase-displaying nanoparticles efficiently consume lactate in the tumor microenvironment to effectively suppress tumor growth

The aggressive proliferation of tumor cells often requires increased glucose uptake and excessive anaerobic glycolysis, leading to the massive production and secretion of lactate to form a unique tumor microenvironment (TME). Therefore, regulating appropriate lactate levels in the TME would be a pro...

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Detalles Bibliográficos
Autores principales: Choi, Hyukjun, Yeo, Mirae, Kang, Yujin, Kim, Hyo Jeong, Park, Seong Guk, Jang, Eunjung, Park, Sung Ho, Kim, Eunhee, Kang, Sebyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811728/
https://www.ncbi.nlm.nih.gov/pubmed/36597089
http://dx.doi.org/10.1186/s12951-022-01762-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811728/
https://www.ncbi.nlm.nih.gov/pubmed/36597089
http://dx.doi.org/10.1186/s12951-022-01762-6

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