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Lactate oxidase/catalase-displaying nanoparticles efficiently consume lactate in the tumor microenvironment to effectively suppress tumor growth
The aggressive proliferation of tumor cells often requires increased glucose uptake and excessive anaerobic glycolysis, leading to the massive production and secretion of lactate to form a unique tumor microenvironment (TME). Therefore, regulating appropriate lactate levels in the TME would be a pro...
Autores principales: | Choi, Hyukjun, Yeo, Mirae, Kang, Yujin, Kim, Hyo Jeong, Park, Seong Guk, Jang, Eunjung, Park, Sung Ho, Kim, Eunhee, Kang, Sebyung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811728/ https://www.ncbi.nlm.nih.gov/pubmed/36597089 http://dx.doi.org/10.1186/s12951-022-01762-6 |
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