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Single-cell DNA methylation sequencing by combinatorial indexing and enzymatic DNA methylation conversion
BACKGROUND: DNA methylation is a critical molecular mark involved in cellular differentiation and cell-specific processes. Single-cell whole genome DNA methylation profiling methods hold great potential to resolve the DNA methylation profiles of individual cell-types. Here we present a method that c...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811750/ https://www.ncbi.nlm.nih.gov/pubmed/36600255 http://dx.doi.org/10.1186/s13578-022-00938-9 |