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Single-cell DNA methylation sequencing by combinatorial indexing and enzymatic DNA methylation conversion

BACKGROUND: DNA methylation is a critical molecular mark involved in cellular differentiation and cell-specific processes. Single-cell whole genome DNA methylation profiling methods hold great potential to resolve the DNA methylation profiles of individual cell-types. Here we present a method that c...

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Detalles Bibliográficos
Autores principales: Chatterton, Zac, Lamichhane, Praves, Ahmadi Rastegar, Diba, Fitzpatrick, Lauren, Lebhar, Hélène, Marquis, Christopher, Halliday, Glenda, Kwok, John B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811750/
https://www.ncbi.nlm.nih.gov/pubmed/36600255
http://dx.doi.org/10.1186/s13578-022-00938-9