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Delayed NLRP3 inflammasome inhibition ameliorates subacute stroke progression in mice

BACKGROUND: Ischemic stroke immediately evokes a strong neuro-inflammatory response within the vascular compartment, which contributes to primary infarct development under vessel occlusion as well as further infarct growth despite recanalization, referred to as ischemia/reperfusion injury. Later, in...

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Detalles Bibliográficos
Autores principales: Bellut, Maximilian, Bieber, Michael, Kraft, Peter, Weber, Alexander N. R., Stoll, Guido, Schuhmann, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811791/
https://www.ncbi.nlm.nih.gov/pubmed/36600259
http://dx.doi.org/10.1186/s12974-022-02674-w