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A gene based combination test using GWAS summary data

BACKGROUND: Gene-based association tests provide a useful alternative and complement to the usual single marker association tests, especially in genome-wide association studies (GWAS). The way of weighting for variants in a gene plays an important role in boosting the power of a gene-based associati...

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Detalles Bibliográficos
Autores principales: Zhang, Jianjun, Liang, Xiaoyu, Gonzales, Samantha, Liu, Jianguo, Gao, Xiaoyi Raymond, Wang, Xuexia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811798/
https://www.ncbi.nlm.nih.gov/pubmed/36597047
http://dx.doi.org/10.1186/s12859-022-05114-x