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NUF2 overexpression contributes to epithelial ovarian cancer progression via ERBB3-mediated PI3K-AKT and MAPK signaling axes

INTRODUCTION: NDC80 kinetochore complex component (NUF2) is upregulated and plays an important role in various human cancers. However, the function and mechanism of NUF2 in epithelial ovarian cancer (EOC) remain unclear. METHODS: NUF2 expression was detected in EOC tissues and cell lines. The effect...

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Detalles Bibliográficos
Autores principales: Leng, Ruobing, Meng, Yunfang, Sun, Xiaomei, Zhao, Yingzi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811817/
https://www.ncbi.nlm.nih.gov/pubmed/36620547
http://dx.doi.org/10.3389/fonc.2022.1057198