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Regulation of RNA localization during oocyte maturation by dynamic RNA-ER association and remodeling of the ER

Asymmetric localization of mRNAs is crucial for cell polarity and cell fate determination. By performing fractionation RNA-seq, we report here that a large number of maternal RNAs are associated with the ER in Xenopus oocytes but are released into the cytosol after oocyte maturation. We provide evid...

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Detalles Bibliográficos
Autores principales: Hwang, Hyojeong, Yun, Seongmin, Arcanjo, Rachel Braz, Divyanshi, Chen, Sijie, Mei, Wenyan, Nowak, Romana A., Kwon, Taejoon, Yang, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811979/
https://www.ncbi.nlm.nih.gov/pubmed/36516762
http://dx.doi.org/10.1016/j.celrep.2022.111802