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Dishevelled phase separation promotes Wnt signalosome assembly and destruction complex disassembly
The amplitude of Wnt/β-catenin signaling is precisely controlled by the assembly of the cell surface–localized Wnt receptor signalosome and the cytosolic β-catenin destruction complex. How these two distinct complexes are coordinately controlled remains largely unknown. Here, we demonstrated that th...
Autores principales: | Kang, Kexin, Shi, Qiaoni, Wang, Xu, Chen, Ye-Guang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9811998/ https://www.ncbi.nlm.nih.gov/pubmed/36342472 http://dx.doi.org/10.1083/jcb.202205069 |
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