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Gene Fusion Detection and Characterization in Long-Read Cancer Transcriptome Sequencing Data with FusionSeeker

Gene fusions are prevalent in a wide array of cancer types with different frequencies. Long-read transcriptome sequencing technologies, such as PacBio, Iso-Seq, and Nanopore direct RNA sequencing, provide full-length transcript sequencing reads, which could facilitate detection of gene fusions. In t...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Wang, Yiqing, Chen, Weisheng, Tan, Zhengzhi, Song, Yuwei, Chen, Herbert, Chong, Zechen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812290/
https://www.ncbi.nlm.nih.gov/pubmed/36318117
http://dx.doi.org/10.1158/0008-5472.CAN-22-1628