Metformin protects trabecular meshwork against oxidative injury via activating integrin/ROCK signals

This study aimed to investigate the protective effect of metformin on trabecular meshwork (TM) and explore its molecular mechanisms in vivo and in vitro. Ocular hypertension (OHT) mouse models were induced with dexamethasone and further treated with metformin to determine the intraocular pressure (I...

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Detalles Bibliográficos
Autores principales: Xu, Lijuan, Zhang, Xinyao, Zhao, Yin, Gang, Xiaorui, Zhou, Tao, Han, Jialing, Cao, Yang, Qi, Binyan, Song, Shuning, Wang, Xiaojie, Liang, Yuanbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812404/
https://www.ncbi.nlm.nih.gov/pubmed/36598818
http://dx.doi.org/10.7554/eLife.81198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812404/
https://www.ncbi.nlm.nih.gov/pubmed/36598818
http://dx.doi.org/10.7554/eLife.81198

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