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Structure and Function of Cationic and Ionizable Lipids for Nucleic Acid Delivery

Hereditary genetic diseases, cancer, and infectious diseases are affecting global health and become major health issues, but the treatment development remains challenging. Gene therapies using DNA plasmid, RNAi, miRNA, mRNA, and gene editing hold great promise. Lipid nanoparticle (LNP) delivery tech...

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Detalles Bibliográficos
Autores principales: Sun, Da, Lu, Zheng-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812548/
https://www.ncbi.nlm.nih.gov/pubmed/36600047
http://dx.doi.org/10.1007/s11095-022-03460-2