The role of Phosphodiesterase-1 and its natural product inhibitors in Alzheimer’s disease: A review

Phosphodiesterase-1 (PDE1) is a versatile enzyme that has surprisingly received considerable attention as a possible therapeutic target in Alzheimer’s disease (AD) because it maintains the homeostasis of 3ʹ,5ʹ-cyclic adenosine monophosphate (cAMP) and 3ʹ,5ʹ-cyclic guanosine monophosphate (cGMP) in t...

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Detalles Bibliográficos
Autores principales: Ahmad, Nazir, Lesa, Kaisun Nesa, Sudarmanto, Ari, Fakhrudin, Nanang, Ikawati, Zullies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812569/
https://www.ncbi.nlm.nih.gov/pubmed/36618909
http://dx.doi.org/10.3389/fphar.2022.1070677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812569/
https://www.ncbi.nlm.nih.gov/pubmed/36618909
http://dx.doi.org/10.3389/fphar.2022.1070677

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