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Multigene Panel Testing Yields High Rates of Clinically Actionable Variants Among Patients With Colorectal Cancer

Whether germline multigene panel testing (MGPT) should be performed in all individuals with colorectal cancer (CRC) remains uncertain. Therefore, we aimed to determine the yield and potential clinical impact of MGPT across a large, diverse CRC cohort. METHODS: This was a retrospective cohort study o...

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Detalles Bibliográficos
Autores principales: Coughlin, Sarah E., Heald, Brandie, Clark, Dana Farengo, Nielsen, Sarah M., Hatchell, Kathryn E., Esplin, Edward D., Katona, Bryson W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812641/
https://www.ncbi.nlm.nih.gov/pubmed/36370464
http://dx.doi.org/10.1200/PO.22.00517