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A positive feedback loop of heparanase/syndecan1/nerve growth factor regulates cancer pain progression

BACKGROUND: The purpose of this research was to assess the role of heparanase (HPSE)/syndecan1 (SDC1)/nerve growth factor (NGF) on cancer pain from melanoma. METHODS: The influence of HPSE on the biological function of melanoma cells and cancer pain in a mouse model was evaluated. Immunohistochemica...

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Detalles Bibliográficos
Autores principales: Su, Xiaohu, Wang, Bingwu, Zhou, Zhaoyun, Li, Zixian, Tong, Song, Chen, Simin, Zhang, Nan, Liu, Su, Zhang, Maoyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812689/
https://www.ncbi.nlm.nih.gov/pubmed/36536517
http://dx.doi.org/10.3344/kjp.22277