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The mechanism of human neural stem cell secretomes improves neuropathic pain and locomotor function in spinal cord injury rat models: through antioxidant, anti-inflammatory, anti-matrix degradation, and neurotrophic activities

BACKGROUND: Globally, spinal cord injury (SCI) results in a big burden, including 90% suffering permanent disability, and 60%–69% experiencing neuropathic pain. The main causes are oxidative stress, inflammation, and degeneration. The efficacy of the stem cell secretome is promising, but the role of...

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Detalles Bibliográficos
Autores principales: Semita, I Nyoman, Utomo, Dwikora Novembri, Suroto, Heri, Sudiana, I Ketut, Gandi, Parama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812698/
https://www.ncbi.nlm.nih.gov/pubmed/36549874
http://dx.doi.org/10.3344/kjp.22279