Imbalance in the spinal serotonergic pathway induces aggravation of mechanical allodynia and microglial activation in carrageenan inflammation

BACKGROUND: This study investigated the effect of an excess and a deficit of spinal 5-hydroxytryptamine (5-HT) on the mechanical allodynia and neuroglia activation in a rodent pain model of carrageenan inflammation. METHODS: Male Sprague–Dawley rats were implanted with an intrathecal (i.t.) catheter...

Descripción completa

Detalles Bibliográficos
Autores principales: Jin, Junxiu, Kang, Dong Ho, Jeon, Jin, Lee, Hyung Gon, Kim, Woong Mo, Yoon, Myung Ha, Choi, Jeong Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pain Society 2023
Materias:
Experimental Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812699/
https://www.ncbi.nlm.nih.gov/pubmed/36581598
http://dx.doi.org/10.3344/kjp.22297

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812699/
https://www.ncbi.nlm.nih.gov/pubmed/36581598
http://dx.doi.org/10.3344/kjp.22297

Ejemplares similares