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Chemogenetic activation of astrocytes promotes remyelination and restores cognitive deficits in visceral hypersensitive rats
Using a well-established chronic visceral hypersensitivity (VH) rat model, we characterized the decrease of myelin basic protein, reduced number of mature oligodendrocytes (OLs), and hypomyelination in the anterior cingulate cortex (ACC). The results of rat gambling test showed impaired decision-mak...
Autores principales: | Hasan, Mahadi, Lei, Zhuogui, Akter, Mastura, Iqbal, Zafar, Usaila, Faeeqa, Ramkrishnan, Aruna Surendran, Li, Ying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812719/ https://www.ncbi.nlm.nih.gov/pubmed/36619970 http://dx.doi.org/10.1016/j.isci.2022.105840 |
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