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Mitophagy in Alzheimer’s disease: Molecular defects and therapeutic approaches

Mitochondrial dysfunctions are central players in Alzheimer’s disease (AD). In addition, impairments in mitophagy, the process of selective mitochondrial degradation by autophagy leading to a gradual accumulation of defective mitochondria, have also been reported to occur in AD. We provide an update...

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Detalles Bibliográficos
Autores principales: Mary, Arnaud, Eysert, Fanny, Checler, Frédéric, Chami, Mounia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812780/
https://www.ncbi.nlm.nih.gov/pubmed/35665766
http://dx.doi.org/10.1038/s41380-022-01631-6