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Hypodopaminergic state of the nigrostriatal pathway drives compulsive alcohol use

The neurobiological mechanisms underlying compulsive alcohol use, a cardinal feature of alcohol use disorder, remain elusive. The key modulator of motivational processes, dopamine (DA), is suspected to play an important role in this pathology, but its exact role remains to be determined. Here, we fo...

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Detalles Bibliográficos
Autores principales: Goutaudier, Raphaël, Joly, Fanny, Mallet, David, Bartolomucci, Magali, Guicherd, Denis, Carcenac, Carole, Vossier, Frédérique, Dufourd, Thibault, Boulet, Sabrina, Deransart, Colin, Chovelon, Benoit, Carnicella, Sebastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812783/
https://www.ncbi.nlm.nih.gov/pubmed/36376463
http://dx.doi.org/10.1038/s41380-022-01848-5