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Hypodopaminergic state of the nigrostriatal pathway drives compulsive alcohol use
The neurobiological mechanisms underlying compulsive alcohol use, a cardinal feature of alcohol use disorder, remain elusive. The key modulator of motivational processes, dopamine (DA), is suspected to play an important role in this pathology, but its exact role remains to be determined. Here, we fo...
Autores principales: | Goutaudier, Raphaël, Joly, Fanny, Mallet, David, Bartolomucci, Magali, Guicherd, Denis, Carcenac, Carole, Vossier, Frédérique, Dufourd, Thibault, Boulet, Sabrina, Deransart, Colin, Chovelon, Benoit, Carnicella, Sebastien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812783/ https://www.ncbi.nlm.nih.gov/pubmed/36376463 http://dx.doi.org/10.1038/s41380-022-01848-5 |
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