Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

Tissue regeneration requires coordination between resident stem cells and local niche cells(1,2). Here we identify that senescent cells are integral components of the skeletal muscle regenerative niche that repress regeneration at all stages of life. The technical limitation of senescent-cell scarci...

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Detalles Bibliográficos
Autores principales: Moiseeva, Victoria, Cisneros, Andrés, Sica, Valentina, Deryagin, Oleg, Lai, Yiwei, Jung, Sascha, Andrés, Eva, An, Juan, Segalés, Jessica, Ortet, Laura, Lukesova, Vera, Volpe, Giacomo, Benguria, Alberto, Dopazo, Ana, Benitah, Salvador Aznar, Urano, Yasuteru, del Sol, Antonio, Esteban, Miguel A., Ohkawa, Yasuyuki, Serrano, Antonio L., Perdiguero, Eusebio, Muñoz-Cánoves, Pura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812788/
https://www.ncbi.nlm.nih.gov/pubmed/36544018
http://dx.doi.org/10.1038/s41586-022-05535-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812788/
https://www.ncbi.nlm.nih.gov/pubmed/36544018
http://dx.doi.org/10.1038/s41586-022-05535-x

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