Persistent increase of accumbens cocaine ensemble excitability induced by IRK downregulation after withdrawal mediates the incubation of cocaine craving

The incubation phenomenon, cue-induced drug craving progressively increasing over prolonged withdrawal, accounts for persistent relapse, leading to a dilemma in the treatment of cocaine addiction. The role of neuronal ensembles activated by initial cocaine experience in the incubation phenomenon was...

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Detalles Bibliográficos
Autores principales: He, Guanhong, Huai, Ziqing, Jiang, Changyou, Huang, Bing, Tian, Zhen, Le, Qiumin, Fan, Guangyuan, Li, Haibo, Wang, Feifei, Ma, Lan, Liu, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Immediate Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812793/
https://www.ncbi.nlm.nih.gov/pubmed/36481931
http://dx.doi.org/10.1038/s41380-022-01884-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812793/
https://www.ncbi.nlm.nih.gov/pubmed/36481931
http://dx.doi.org/10.1038/s41380-022-01884-1

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