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Differential vulnerability of adult neurogenic niches to dosage of the neurodevelopmental-disorder linked gene Foxg1

The transcription factor FOXG1 serves pleiotropic functions in brain development ranging from the regulation of precursor proliferation to the control of cortical circuit formation. Loss-of-function mutations and duplications of FOXG1 are associated with neurodevelopmental disorders in humans illust...

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Detalles Bibliográficos
Autores principales: Schäffner, Iris, Wittmann, Marie-Theres, Vogel, Tanja, Lie, D. Chichung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812795/
https://www.ncbi.nlm.nih.gov/pubmed/35318461
http://dx.doi.org/10.1038/s41380-022-01497-8