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Differential vulnerability of adult neurogenic niches to dosage of the neurodevelopmental-disorder linked gene Foxg1
The transcription factor FOXG1 serves pleiotropic functions in brain development ranging from the regulation of precursor proliferation to the control of cortical circuit formation. Loss-of-function mutations and duplications of FOXG1 are associated with neurodevelopmental disorders in humans illust...
Autores principales: | Schäffner, Iris, Wittmann, Marie-Theres, Vogel, Tanja, Lie, D. Chichung |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812795/ https://www.ncbi.nlm.nih.gov/pubmed/35318461 http://dx.doi.org/10.1038/s41380-022-01497-8 |
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