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EZH2 promotes angiogenesis in peritoneal dialysis by epigenetically activating SP4 expression in the IL-6/sIL-6R signalling pathway

Background: Interleukin-6 (IL-6)/soluble IL-6 receptor (sIL-6R) promotes peritoneal angiogenesis by stimulating SP4-mediated vascular endothelial growth factor (VEGF) production in peritoneal dialysis (PD). Moreover, histone methyltransferase enhancer of zeste homologue 2 (EZH2) is involved in IL-6/...

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Detalles Bibliográficos
Autores principales: Zhu, Nan, Guan, Haochen, Wang, Xuan, Zhang, Yueyue, Gu, Lijie, Jia, Jieshuang, Wang, Ling, Yuan, Weijie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812808/
https://www.ncbi.nlm.nih.gov/pubmed/36619221
http://dx.doi.org/10.7150/ijms.78428