ERBB and P‐glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P‐glycoprotein

Chemotherapy resistance is a persistent clinical problem in relapsed high‐risk neuroblastomas. We tested a panel of 15 drugs for sensitization of neuroblastoma cells to the conventional chemotherapeutic vincristine, identifying tariquidar, an inhibitor of the transmembrane pump P‐glycoprotein (P‐gp/...

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Detalles Bibliográficos
Autores principales: Rösch, Lisa, Herter, Sonja, Najafi, Sara, Ridinger, Johannes, Peterziel, Heike, Cinatl, Jindrich, Jones, David T. W., Michaelis, Martin, Witt, Olaf, Oehme, Ina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812835/
https://www.ncbi.nlm.nih.gov/pubmed/36181342
http://dx.doi.org/10.1002/1878-0261.13318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812835/
https://www.ncbi.nlm.nih.gov/pubmed/36181342
http://dx.doi.org/10.1002/1878-0261.13318

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