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Distinct p53 phosphorylation patterns in chronic lymphocytic leukemia patients are reflected in the activation of circumjacent pathways upon DNA damage

TP53 gene abnormalities represent the most important biomarker in chronic lymphocytic leukemia (CLL). Altered protein modifications could also influence p53 function, even in the wild‐type protein. We assessed the impact of p53 protein phosphorylations on p53 functions as an alternative inactivation...

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Detalles Bibliográficos
Autores principales: Mancikova, Veronika, Pesova, Michaela, Pavlova, Sarka, Helma, Robert, Zavacka, Kristyna, Hejret, Vaclav, Taus, Petr, Hynst, Jakub, Plevova, Karla, Malcikova, Jitka, Pospisilova, Sarka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812841/
https://www.ncbi.nlm.nih.gov/pubmed/36334078
http://dx.doi.org/10.1002/1878-0261.13337