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IL-4Rα signalling in B cells and T cells play differential roles in acute and chronic atopic dermatitis

Atopic dermatitis (AD) is a common pruritic inflammatory skin disease with complex environmental and genetic predisposing factors. Primary skin barrier dysfunction and aberrant T helper 2 (TH2) responses to common allergens, together with increased serum IgE antibodies, characterise the disease. B a...

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Detalles Bibliográficos
Autores principales: Scibiorek, Martyna, Mthembu, Nontobeko, Mangali, Sandisiwe, Ngomti, Amkele, Ikwegbue, Paul, Brombacher, Frank, Hadebe, Sabelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9812985/
https://www.ncbi.nlm.nih.gov/pubmed/36599893
http://dx.doi.org/10.1038/s41598-022-26637-6