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TRIM59 promotes steatosis and ferroptosis in non-alcoholic fatty liver disease via enhancing GPX4 ubiquitination

Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease around the world. However, no specific medicine has been approved for NAFLD treatment. Our study was conducted to explore the role and mechanism of TRIM59 in NAFLD, aiming to provide a novel target for NAFLD treatment. Here,...

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Detalles Bibliográficos
Autores principales: Zhang, Jingxian, Xie, Haina, Yao, Jun, Jin, Wenye, Pan, Huijie, Pan, Zhiqiang, Xie, Dongyu, Xie, Donghao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813033/
https://www.ncbi.nlm.nih.gov/pubmed/36417114
http://dx.doi.org/10.1007/s13577-022-00820-3