Cargando…

Improving clinical trial design using interpretable machine learning based prediction of early trial termination

This study proposes using a machine learning pipeline to optimise clinical trial design. The goal is to predict early termination probability of clinical trials using machine learning modelling, and to understand feature contributions driving early termination. This will inform further suggestions t...

Descripción completa

Detalles Bibliográficos
Autores principales: Kavalci, Ece, Hartshorn, Anthony
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813129/
https://www.ncbi.nlm.nih.gov/pubmed/36599880
http://dx.doi.org/10.1038/s41598-023-27416-7