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Intratumoral T cell depletion following neoadjuvant chemotherapy in patients with muscle-invasive bladder cancer is associated with poor clinical outcome

BACKGROUND: Whereas neoadjuvant cisplatin-based chemotherapy (NAC) followed by a radical cystectomy remains the standard treatment for patients with muscle-invasive bladder cancer (MIBC), increasing evidence suggests that checkpoint inhibitors, either alone or in combination with chemotherapy, are e...

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Detalles Bibliográficos
Autores principales: van Wilpe, Sandra, Sultan, Shabaz, Gorris, Mark A. J., Somford, Diederik M., Kusters-Vandevelde, Heidi V. N., Koornstra, Rutger H. T., Gerritsen, Winald R., Simons, Michiel, van der Heijden, Antoine G., de Vries, I. Jolanda M., Mehra, Niven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813168/
https://www.ncbi.nlm.nih.gov/pubmed/35771253
http://dx.doi.org/10.1007/s00262-022-03234-0