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Novel CSF1R-positive tenosynovial giant cell tumor cell lines and their pexidartinib (PLX3397) and sotuletinib (BLZ945)-induced apoptosis

Tenosynovial giant cell tumor (TGCT) is a mesenchymal tumor derived from the synovium of the tendon sheath and joints, most frequently in the large joints. The standard of care for TGCTs is surgical resection. A new targeting approach for treating TGCTs has emerged from studies on the role of the CS...

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Detalles Bibliográficos
Autores principales: Thongchot, Suyanee, Duangkaew, Supani, Yotchai, Wasan, Maungsomboon, Sorranart, Phimolsarnti, Rapin, Asavamongkolkul, Apichat, Thuwajit, Peti, Thuwajit, Chanitra, Chandhanayingyong, Chandhanarat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813176/
https://www.ncbi.nlm.nih.gov/pubmed/36456782
http://dx.doi.org/10.1007/s13577-022-00823-0