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Sequential therapy with once-weekly teriparatide injection followed by alendronate versus monotherapy with alendronate alone in patients at high risk of osteoporotic fracture: final results of the Japanese Osteoporosis Intervention Trial-05

SUMMARY: In this randomized, controlled trial, sequential therapy with once-weekly subcutaneous injection of teriparatide for 72 weeks, followed by alendronate for 48 weeks resulted in a significantly lower incidence of morphometric vertebral fracture than monotherapy with alendronate for 120 weeks...

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Detalles Bibliográficos
Autores principales: Mori, Satoshi, Hagino, Hiroshi, Sugimoto, Toshitsugu, Tanaka, Shiro, Mitomo, Yuji, Takahashi, Kaito, Sone, Teruki, Nakamura, Toshitaka, Soen, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer London 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813198/
https://www.ncbi.nlm.nih.gov/pubmed/36239756
http://dx.doi.org/10.1007/s00198-022-06570-0