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CCR7/dendritic cell axis mediates early bacterial dissemination in Orientia tsutsugamushi-infected mice

Scrub typhus is a life-threatening zoonosis caused by the obligate intracellular bacterium Orientia tsutsugamushi (Ot) that is transmitted by the infected larvae of trombiculid mites. However, the mechanism by which Ot disseminates from the bite site to visceral organs remains unclear; host innate i...

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Detalles Bibliográficos
Autores principales: Liang, Yuejin, Wang, Hui, Gonzales, Casey, Thiriot, Joseph, Sunyakumthorn, Piyanate, Melby, Peter C., Sun, Jiaren, Soong, Lynn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9813216/
https://www.ncbi.nlm.nih.gov/pubmed/36618364
http://dx.doi.org/10.3389/fimmu.2022.1061031